74 YM WITH LOSS OF SPEECH , URINARY INCONTINENCE

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I have been given this case to solve in an attempt to understand the topic of  " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan

C/O

1.  loss of speech since 10 days 

2. Urinary incontinence since 10 days

HOPI

Patient was apparently asymptomatic 25 years back 

1.25 years back he went to Bombay at her sisters home while returning back to kondaram got fever for a 1 week which relieved with medication and on routine investigations was found to have Diabetes Mellitus for which he was started on ORAL HYPOGLYCAEMC DRUGS

2. Patient was asymptomatic 17 years then he developed pedal Edema till knees, yellowish discolouration of eyes and shortness of breadth on exertion for which he got admitted to hospital for 8 days and was managed conservatively. 

3. Patient was asymptomatic for 7 years back then 10 years back he developed, history of fever which was low grade associated with evening rise of temperature and cough for 10 days 

Diagnosed with ? Sputum positive Tuberculosis and was treated with ATT for 2 years 

4. He was asymptomatic till 3years back he then developed pain in the right loin for 10 days for which they went to a local hospital and were told as having renal calculi and was kept on conservative management but pain did not subside pain didn’t subsided even on using medication for 6 days and then ?stent /?foleys was placed ,but still his pain didn’t subsided associated with new onset fever,and then they removed the placed stent ,but still the pain at the right loin persisted a surgery was done?lithotripsy ,and then again went to other hospital as they were told that calculi wasn’t removed completely and again stent was placed >>it got infected and seen as pus filled mass at the right loin and then surgery was done and pain got relieved

5. Patient was alright till 4 months then he had small abrasion / small crack over left toe initially And then he got injury over the same finger by accidentally hitting it to a wall lead to > swelling —>backish discolouration in 8 days —> amputation of 2nd toe 


At the same time patient developed dragging type of pain in the left hand for which investigations were done and treated with muscle relaxants and PPI . 

After 2 days had history of fall ( due to imbalance) at 2:00am in night when he got up to go to washroom for which went to hospital and was found to have ? intertrochantric fracture ? Hemiarthroplasty was done 

During postoperative period patient had episodes of altered sensorium over a transient period , for which MRI/CT was done was told to have mass in the brain (? Neoplasm) 

and the episodes of altered sensorium/hallucinations once/twice in a week(Eg:He mistakened the hanged clothes as persons,and used to talk with persons who expired)

And 2 months ago ,he developed pain in the right hypochondrium dragging type and got admitted in hospital and was treated conservatively for 10 days,and told as having ?cholelithiasis ,

10 days ago in the afternoon he ate rice and at 3:00pm he had a pomegranate fruit and at 4:00pm he was sleeping on the bed and when his wife called her,he had no response on calling him(lost his speech),(eyes open )and she thought it as hypoglycaemic episode and poured sugar in his mouth but he was not having it,and at the same time he had involuntary rolling over the bed and stiffened mouth(unable to open) and had involuntary micturition at that time and rmp arrived and his Bp and grbs was normal and they took them to hospital and during travelling he had deviation of mouth to right, they(attenders)thought it as hemiparesis, and at hospital his SBP was 240mmHg, and on medication the deviation got corrected and on day 2 of admission due to decrease in saturation ,patient was intubated on 8-7-2023 and extubated on 14-07-2023.

Post extubation,no return of his speech and there were absent tongue moments also.



PAST HISTORY- 

K/c/o DM since 15 years on OHA 

Shifted to insulin 1 year back 

K/c/o CKD since 4 month and on conservative management 

On regular checkup checkup was diagnosed as having HTN since 2 years and is on regular medication. 


FAMILY HISTORY- 

No significant family history 


PERSONAL HISTORY- 


Diet - mixed 

Previously he used to have,gatka in morning and rice in afternoon and night ,but since 4 months gatka in the morning ,rice afternoon ,java at 3pm and at 8pm.

Appetite - decreased since 10 days 

Bowel and bladder- constipation since 15 days 

Addictions- chronic alcoholic since 30 years , stopped 3 years ago , smoker for 20 years stopped 2 years ago 


GENERAL EXAMINATION-

Patient is conscious, coherent and cooperative

Orientation 

Moderately built and nourished                  Pallor- absent 

Icterus-absent 

Cyanosis-absent 

Lymphadenopathy-absent 

Edema-absent 



At the Time of admission 

VITALS

BP- 150/70 mmHg 

PR-98 bpm

GCS- E4V1M6

RR- 18cpm

Investigations- (09/07/2023)



MRI BRAIN 
Questions around this patient :
1)cause of his sudden aphasia,?
2)If the mass in the frontal lobe is the cause ,why would  it cause sudden aphasia?
3)cause for his hypertonia of his upperlimbs ?
ANSWERS

1) Compression of motor and sensory speech areas due to focal raised ICT caused by the focal lesion 

2) Sudden rise of focal pressure such as bleed into the mass or infarct into the mass or if the mass was a living parasite, it's sudden death and consequent inflammation 

4) Compression of the inhibitory interneurons in the UMN pyramidal fibers traversing the subcortical areas of the frontal lobe as well as brain stem

SYSTEMIC EXAMINATION
Respiratory system
Patient examined in sitting position
Inspection:-
oral cavity- Normal ,nose- normal ,pharynx-normal 
Shape of chest - normal
Chest movements : bilaterally symmetrical
Trachea is central in position.
Palpation:-
All inspiratory findings are confirmed
Trachea central in position
Apical impulse in left 5th ICS, 
Chest movements bilaterally symmetrical 
AUSCULTATION 
BAE+,  NVBS

Cardiovascular system-
JVP - not raised 
Visible pulsations: absent 
Apical impulse : left 5th intercostal space in midclavicular line.
Thrills -absent 
S1, S2 - heart sounds heard 
Pericardial rub - absent

Abdominal examination - 

INSPECTION-

Shape - round large with no distension 

Umbilicus - inverted 

Equal symmetrical movements in all quadrants with respiration 

No visible pulsations , palpations , dilated veins or localised swelling

PALPITATION - 

No local rise of temperature 

No tenderness 

No organometaly 

PERCUSSION- liver dullness heard at 5th intercostal space 

AUSCULTATION

Bowel sounds present 

No bruit heard 

Central nervous system- 

HMF- 
Pt is conscious 
Speech- slurred 

Spinothalmic

                           RIGHT.     LEFT

1. Crude touch-    +             +

2. Pain-                  +             +

3.Temperature-     +             +


Posterior Coloumn

1. Fine touch          +             +

2.Vibration             Felt         Felt

( over bony prominence ) 

                               

MOTOR EXAMINATION 

Tone  

UL-                        Increased            N

LL-                         Increased            N


Power 

UL-                       4/5        4/5

LL-                       4/5         4/5


Reflexs               

B                           +3          +3

T                           +2          +2

S                            -            -

K                           +2           +2 

A                            -             -

Plantars            Flexor            Flexor

INVESTION--On 18/07/23
FASTING BLOOD SUGAR - 139mg/dl

On 19/07/23


BLOOD UREA - 50mg/dL
SERUM CREATININE-2.3mg/dl


SERUM URIC ACID - 7.5 mg%

On 20/07/23

PROVISIONAL DIAGNOSIS- 
? Aphasia secondary to Rt frontal lobe mass 
? Pneumonia secondary to aspiration/ infection

TREATMENT- 
1. Ryles Tube feeding 
2. Inj Amoxicillin 625 mg iv/tid 
3. Inj pan 40 mg iv/od
4. Inj Lasix 40 mg iv/BD
( if SBP>110 mmHg)
5. Inj HAI AC/tid 
6. Tab Cinod 10 mg po/od 

7. Inj Erythropoietin 4000 IU /sc/once a week 


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