51 year old female with meningitis



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A 55 YR OLD FEMALE WITH FEVER , NECK STIFFNESS AND HEADACHE
 I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan.

HALL TICKET ::-1701006147

Final practical exam LONG CASE:-



CHIEF COMPLAINTS:

 A 55 yr old female who is house maid by occupation came to the hospital with chief complaints- 

Fever since 5 days 

Neck stiffness since 5 days 

History of present illness:- 

- Patient was apparently asymptomatic 5 days back then she had fever which is sudden in onset and continuous type and relieved on medication and associated with tremors.
Complaints of bilateral knee joint pains .
Negative history:-
Fever not associated with chills and rigors. No h/o cold ,cough ,loose stools , abdominal pain , breathlessness, PND , orthopnoea. No history of burning micturition, increased frequency of micturition. 

- There is h/o headache from 25 days but it got aggravated since 5 days which is insidious in onset and progressive for which she took medication but not relieved. No aggravating and relieving factors . - History of neck stiffness since 5 days.
- History of vomiting 3 days back ,1 episode which is not projectile ,non bilious ,content is food particles .

PAST HISTORY:- 
No history of similar complaints in the past.
Medical illness - Not a known case of diabetes , hypertension, asthma, TB, Thyroid .
•7 yrs back she had history of CVA where both upper and lower limbs are paralysed and took some medication.
she took allopathy medicine 6 months back and she got recovered.
•Surgical history- hysterectomy done 25 yrs back .

FAMILY HISTORY:-

No similar complaints inthe family 
No history of diabetes, hypertension,TB ,asthma.

PERSONAL HISTORY:- 

Diet - mixed 
Appetite - lost
Sleep - adequate 
Bowel and bladder- regular bladder and constipation is present .
No addictions and allergies.



GENERAL EXAMINATION:-

Patient is conscious, coherent, coperative. Moderately built moderately nourished.

No pallor, icterus, cyanosis, clubbing, generalised lymphadenopathy, generalised edema.






VITALS: 

Temperature: 99°F
Pulse rate: 78bpm
Resp rate:15cpm
BP:110/70mmhg
Spo2:98%

SYSTEMIC EXAMINATION

CENTRAL NERVOUS SYSTEM::-

Higher mental functions

          • conscious

          • oriented to person and place ,time.

          • memory - able to recognize their family members

          • Speech - normal
CRANIAL NERVES examination -

           • 1 - sense of smell present

           • 2- Direct and indirect light reflex present

           • 3,4,6 - no ptosis Or nystagmus

           • 5- corneal reflex present on both sides

           • 7- no deviation of mouth, no loss of nasolabial folds, forehead wrinkling present.

         • 8- able to hear

         • 9,10- uvula not deviated

        • 11- sternocleidomastoid contraction present

        • 12- no tongue deviation

Motor system 

Tone -. Upper limbs 
Tone:   Lower limbs






Inspection - Normal Normal
Palpation - Normal Normal 

Bulk :         right           Left 
 
Arm :-        28cm.         27cm
Forearm:-    20cm        18 cm
Thigh:          33 cm       32cm
Calf:.            25 cm       23 cm





Power : 

Muscles of neck -
• stenocleidomastoid- good
•Nuchal muscles- stiffness present
Slight tenderness present over the neck on examination.

                       Right     Left
Biceps-             5/5        5/5
Triceps-.           5/5        5/5
Brachioradialis-. 5/5      5/5
Tibialis posterior-. 5/5   5/5


Reflexes: right left 
       
Biceps- + +





Triceps- + +





Knee- + +





Ankle - + + 





Babinski sign





Sensory system: Normal

Cerebellar signs : 

Knee - heel incoordination - No
Finger - nose incoordination- No

Meningeal signs - 

 Neck stiffness present .
Kernig's sign - positive
Brudzinki sign - positive




EXAMINATION OF OTHER SYSTEMS


CARDIOVASCULAR SYSTEM: 
 
S1 S2 Heart sounds – normal
No thrills/murmurs

RESPIRATORY SYSTEM:

 Chest symmetrical, No paradoxical movements, Normal vesicular breath sounds heard,
No abnormal/added sound

ABDOMEN:

 Abdomen is soft, non tender,No organomegaly, No ascites.

Provisional diagnosis:VIRAL FEVER with VIRAL MENINGOENCEPHALITIS under evaluation and detected denovo DIABETES MELLITUS type 2.

Investigations:-

GRBS - 100 mg/dl

Hemogram :-


Hb - 13 g/dl
TLC - 3500
N/L/E/M-60/30/2/8
PLT- 2.1 lakh per mm3
FBS- 168**mg/ dl
Hb1 AC -6.9*

Urea- 38
Serum creatinine- 1.0
Uric acid - 4.9
Sodium- 141meq
Pottasium- 4.0
chloride- 1058

Serology 




LFT:

Tb - 1.03
Db- 0.31
SGOT(AST) - 69
SGPT(ALT) - 68
ALP-135
Tp-6.4
Albumin-4.0

CUE:

Albumin +
Sugar - nil 
Pus cells - 6 - 8
Epithelial cells- 3-4
RBC - nil
Casts - nil 

CSF :

Sugar - 81
Protein-12.6
Chloride-113

ABG:

pH - 7.4
Pco2- 29.1
Po2- 88.4
Hco3- 18.0
Sat O2 - 97%

MRI brain :











X Ray - knee joint AP view



X ray Lateral view of skull and neck-





X Ray chest :

ECG






Treatment:-

Inj. CEFTRIAXONE 2 gm/ BD 
Inj.DEXA 6mg/iv/tid
Inj . Vancomycin 1gm/iv
Inj. Pcm 1gm/iv
Tab . Pcm 650 mg 
Tab. Ecospirin 75 mg /po/od
Tab. Atorvas 10 mg /po/od
Syp. Cremaffin plus 30ml/po


On day 2 :-
 
Patient is conscious, coherent, cooperative.

Vitals:-
Temperature: 99°F
Pulse rate: 76bpm
Resp rate:15cpm
BP:130/90mmhg
Spo2:96%

GRBS- 197mg/dl





Treatment-

Inj. CEFTRIAXONE 2 gm/ BD 
Inj.DEXA 6mg/iv/tid
Inj . Vancomycin 1gm/iv
Inj. Pcm 1gm/iv
Tab . Pcm 650 mg 
Tab. Ecospirin 75 mg /po/od
Tab. Atorvas 10 mg /po/od
Syp. Cremaffin plus 30ml/po
Oint.Diclofenac for thigh pain

On day 3:-

Patient is conscious, coherent, cooperative.

Vitals:-
Temperature: 99°F
Pulse rate: 78bpm
Resp rate:16cpm
BP:120/90mmhg
Spo2:96%

GRBS- 190mg/dl

Investigations:-



Treatment-

Inj. CEFTRIAXONE 2 gm/ BD 
Inj.DEXA 6mg/iv/tid
Inj . Vancomycin 1gm/iv
Inj. Pcm 1gm/iv
Tab . Pcm 650 mg 
Tab. Ecospirin 75 mg /po/od
Tab. Atorvas 10 mg /po/od
Syp. Cremaffin plus 30ml/po
Oint.Diclofenac for thigh pain
Inj.pan 40 mg iv /od
Tab. Naproxen 250 mg po/tid.
Flexbenz gel for L/A on thighs


















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